Pin 1 protein
WebOsteoporosis is caused by an imbalance of osteoclast and osteoblast activities and it is characterized by enhanced osteoclast formation and function. Peptidyl-prolyl cis-trans isomerase never in mitosis A (NIMA)-interacting 1 (Pin1) is a key mediator of osteoclast cell-cell fusion via suppression of the dendritic cell-specific transmembrane protein (DC … WebPin1 Protein Overview. Peptidyl-prolyl cis/trans isomerases (PPIases; EC 5.2.1.8), such as PIN1, catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. PIN1 is the only PPIase that specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates.
Pin 1 protein
Did you know?
WebStrikingly, while auxin transport during root initiation is mediated by the redundant activity of multiple PIN proteins, PIN1 is the dominant family member in cotyledon initiation (Benkova et al., 2003; Liu et al., 1993 ). Therefore, localization of PIN1 is particularly informative to define auxin streams that are required for cotyledon initiation. WebMar 13, 2024 · Pin It on Pinterest. Cerrar los ajustes de cookies RGPD. Resumen de privacidad; Cookies estrictamente necesarias; Cookies de terceros; Powered by GDPR Cookie Compliance. Resumen de privacidad. Esta web utiliza cookies para que podamos ofrecerte la mejor experiencia de usuario posible. La información de las cookies se …
WebOct 15, 2005 · Insets show higher magnifications of early time points (A) and low concentrations(B). The legend in B also applies to A. (C,D) Auxin (1 μmol/l 2,4-D) does not induce PIN expression in slr-1 mutants (C) or after induction of axr3 expression in HS::axr3-1 lines (D), as shown by quantitative RT-PCR. Cycloheximide alone induces PIN … WebHowever, the role of Pin1 in cancer remains enigmatic as the gene is located on chromosome 19p13.2, which is a region subject to loss of heterozygosity in several tumors. Since Pin1 protein is frequently under-expressed in kidney cancer, we have explored its role in human clear cell renal cell carcinoma (ccRCC).
WebAug 1, 2014 · Peptidyl-prolyl cis-trans-isomerase (Pin 1 or PPIase) is an endogenous chaperone that regulates the activity of phosphorylated tau protein, APP enzymatic processing, and Ab expression (Wang et al ... WebPIN1 involved in several pathways and played different roles in them. We selected most pathways PIN1 participated on our site, such as RIG-I-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIN1 were listed below.
WebMar 21, 2024 · PIN1 (Peptidylprolyl Cis/Trans Isomerase, NIMA-Interacting 1) is a Protein Coding gene. Diseases associated with PIN1 include Frontotemporal Dementia and Adenoid Cystic Carcinoma . Among its …
WebPIN proteins are the most studied class of auxin efflux carriers that fit to the chemiosmotic theory of auxin transport (Galweiler et al., 1998; Zhou and Luo, 2024). The PIN owes its nomenclature to Arabidopsis pin1 mutant needle-like inflorescence phenotype, devoid of stem and leaves (Galweiler et al., 1998; Okada et al., 1991). dj ironsWebAug 29, 2024 · Pin1 also stabilizes bromodomain-containing protein 4 (BRD4), a transactivator of multiple oncogenes, to promote the proliferation, migration, and invasion of gastric cancer 62. dj ironikWebPIN1 The human parvulin PIN1 (EC 5.2.1.8, 163aa) is a nuclear protein implicated in the regulation of mitosis through interaction with CDC25 and polo-like kinase-1. From: The Dictionary of Cell & Molecular Biology (Fifth Edition), 2013 View all Topics Download as PDF About this page c 正規表現WebMar 16, 2024 · Easy 1-Click Apply (JOHNSON & JOHNSON) Sr Scientist Protein Biomarker Identification and Assay Development job in San Diego, CA. View job description, responsibilities and qualifications. See if you qualify! c 比較 代入WebDec 22, 2024 · Major plasma membrane proteins such as ATPases, aquaporins, and cellulose synthases, as well the auxin transporters AUX/LAX and Nb PIN7, were similar between all samples, also indicating equivalent amounts of plasma membranes ( Fig. 2 B and C and SI Appendix, Table S1 ). dj irpfhttp://jhxhjt.com/sbqo427a.html c 比较两个字符串是否相同WebMay 29, 2015 · Pin1 protein is a peptidyl-prolyl cis-trans isomerase that modulates the activity of a range of proteins involved in cell function. We and others have demonstrated neuronal Pin1 deficits in Alzheimer's disease (AD) and have shown similar deficits in frontotemporal dementia and in aging. Pin1 may, in fact, be a susceptibility factor; others … c 機械語