WebFurthermore, IFI16 protein expression is regulated by post-translational mechanisms that are independent of p53 [37] and IFI204 expression was associated with myoblast, macrophage, myeloid and lymphocytic differentiation [28, 42-44]. Web27 aug. 2024 · Purpose: Thrombospondin 1 ( THBS1) is an endogenous inhibitor of angiogenesis, but it also promotes tumor invasion, metastasis, and immune response in the tumor environment. Previous research has found that THBS1 is highly expressed in many tumors and has a negative correlation with tumor prognosis.
Ifi204 Polyclonal Antibody (PA5-23494)
Web30 mei 2024 · Tumor-associated macrophages (TAMs) contribute to tumor progression through a variety of mechanisms that include promotion of angiogenesis, tumor cell … Web2 jun. 2024 · Thrombospondin-1 (THBS1) is a matrix glycoprotein that can affect fibrosis by activating TGF- β 1, which plays a key role in wound repair and tissue regeneration; therefore, we investigated the effects of THBS1 on the biological function of hypertrophic scar fibroblasts. THBS1 expression was measured in hypertrophic scars and adjacent … fbp of the year
Effect of THBS1 on the Biological Function of Hypertrophic
Web1 dec. 2024 · Macrophages in peritoneal cavity are divided into two subsets, large peritoneal macrophages (LPMs) and small peritoneal macrophages (SPMs), which are defined as F4/80 Hi CD11b + and F4/80 Lo CD11b + cells, respectively [ 16 ]. Small intestinal lamina propria macrophages are defined as F4/80 Hi CD11b Int cells [ 17 ]. Web20 feb. 2015 · We created cGAS, Ifi204, and Sting functional knockouts in RAW264.7 macrophages and demonstrated that cGAS and Ifi204 cooperate to sense dsDNA and activate the STING-dependent type I IFN pathway. WebWhile the role of IFI204 and IFI205 in macrophages has been previously studied,,, nothing was known about IFI207’s function, and we therefore focused on characterizing this PYHIN. To study IFI207 protein expression in macrophages, we generated and validated a rabbit anti-IFI207 peptide antibody ( Figure S1 L). fb plate means