Tīmeklis2014. gada 30. dec. · Notably, approval was granted despite the absence from ezetimibe’s portfolio of studies, demonstrating reductions in hard clinical cardiovascular outcomes, such as myocardial infarction or stroke. By 2006, ezetimibe accounted for >15% of all prescriptions for lipid-lowering medications in the United States, 1 … Tīmeklis2024. gada 17. sept. · Purpose Whether moderate-intensity statins plus ezetimibe could be an alternative to high-intensity statins in patients with atherosclerotic cardiovascular disease is unclear. We compared the risk of adverse cardiovascular events in patients receiving moderate-intensity statins plus ezetimibe vs. high-intensity statins after a …
Ezetimibe and regression of carotid atherosclerosis: importance …
Tīmeklis2024. gada 4. maijs · Objective To compare the impact of ezetimibe and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors on cardiovascular outcomes in … Tīmeklis2016. gada 28. aug. · Benefit of Adding Ezetimibe to Statin Therapy on Cardiovascular Outcomes and Safety in Patients With vs. Without Diabetes: Results from IMPROVE-IT. Circulation 2024;137:1571-82. Bohula EA, Wiviott SD, Giugliano RP, et al. Prevention of Stroke With the Addition of Ezetimibe to Statin Therapy in Patients With Acute … fc wald zh
Ezetimibe and Improving Cardiovascular Outcomes: …
Tīmeklis2024. gada 4. maijs · Adding ezetimibe to PCSK9 inhibitor and statins did not reduce outcomes beyond MID, while adding PCSK9 inhibitor to ezetimibe and statins may reduce stroke (13 per 1000). These effects were consistent in statin-intolerant patients. Among moderate and low cardiovascular risk groups, adding PCSK9 inhibitor or … TīmeklisUse of statin therapy is a key first-line approach in preventing coronary heart disease events and stroke in people at increased risk of developing such complications. Ezetimibe (Ezetrol - MSD-Schering-Plough), the first licensed azetidinone drug, is being promoted as an adjunct to statin therapy to achieve greater reductions in blood … TīmeklisThe primary endpoint was a 3-year composite of cardiovascular death, major cardiovascular events, or nonfatal stroke. Among the 3,780 enrolled patients, 574 (15.2%) were aged ≥75 years. frm3w-2a10 relay