Effects of glucocorticoids on the inner ear
WebThe side effects associated with glucocorticoid treatment, such as osteoporosis, cardiovascular disease, and inflammatory disorders (e.g., Ref. [52] ), have spurred investigations into alternative treatments for steroid-responsive hearing loss. WebSep 18, 2024 · Moreover, glucocorticoids have side effects such as a susceptibility to infections. In otolaryngology—specifically, within the inner ear—surgical and non-surgical pathologies include...
Effects of glucocorticoids on the inner ear
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WebGlucocorticoids / therapeutic use Hearing Loss, Noise-Induced Hearing Loss, Sudden / drug therapy Hearing Loss, Sudden / etiology Hearing Loss, Sudden / physiopathology WebJul 1, 2024 · Studies have revealed the presence of glucocorticoid receptors in the inner ear. The action of corticosteroids in the course of MD is based on their anti-inflammatory …
WebEndogenous glucocorticoids (GC) are known to modulate basic elements of cochlear physiology. These include both noise-induced injury and circadian rhythms. While GC signaling in the cochlea can directly influence auditory transduction via actions on hair cells and spiral ganglion neurons, evidence also indicates that GC signaling exerts effects via … WebThe demonstration of the presence of glucocorticoid receptors in human Inner ear tissues provides a basis to consider the direct effects of glucocorticoid action on select inner …
WebJun 23, 2024 · Ear infection. An ear infection (sometimes called acute otitis media) is an infection of the middle ear, the air-filled space behind the eardrum that contains the tiny vibrating bones of the ear. Children are … WebThe demonstration of the presence of glucocorticoid receptors in human inner ear tissues provides a basis to consider the direct effects of glucocorticoid action on select inner ear cells, rather than assuming a systemic antiinflammatory or immunosuppressive effect during the therapeutic treatment of patients with given inner ear disorders.
WebWe performed an immunohistochemical investigation of the distribution of glucocorticoid receptors (GRs) in the murine inner ear and found that GRs were expressed extensively, but with various degrees of immunoreactivity in different regions. We observed the strongest GR expression in the type III fibrocytes of the spiral ligament.
christmas story slideshowWebJul 4, 2024 · Gastrointestinal (GI) Adverse Effects. Glucocorticoids increase the risk of adverse GI effects, such as gastritis, gastric ulcer formation, and GI bleeding. The use of NSAIDs and glucocorticoids is … christmas story slideWebThe low percentage of severe adverse effects observed in the present study validates the use of corticosteroids for the treatment of inner ear disorders although the authors should not underestimate these rare complications. Background: Because of their anti-inflammatory effects and suppression of the immune system, glucocorticoids have been widely used … christmas story slippers xlWebAdverse effects of glucocorticoid therapy for inner ear disorders The low percentage of severe adverse effects observed in the present study validates the use of corticosteroids for the treatment of inner ear disorders although we … christmas story sequel topsWebBackground: The purpose of this study is to analyse the long-term effects of a 12-week course of topical steroids on adenoid size and its mucus using endoscopy and on middle ear effusion measured by tympanometry. Methods: The study presents an endoscopic choanal assessment of the change in adenoid size (adenoid to choanae ratio, A/C ratio) … christmas story scut farkusWebthe inner ear and systemic autoimmune diseases. A few years later Hilger and Goltz (1951) treated a per-sonwith supposed inflammationinthe earwith corticosteroids and proposed … christmas story soap in mouthWebSep 18, 2024 · Moreover, glucocorticoids have side effects such as a susceptibility to infections. In otolaryngology—specifically, within the inner ear—surgical and non-surgical pathologies include cochlear implantation, stapes surgery, perilymph fistulas and … christmas story slippers